Antibacterials for systemic use; Other antibacterials.
ATC code: J01XX01
Mechanism of action:
Fosfomycin exerts a bactericidal effect on proliferating pathogens by preventing the enzymatic synthesis of the bacterial cell wall. Fosfomycin inhibits the first stage of intracellular bacterial cell wall synthesis by blocking peptidoglycan synthesis.
Fosfomycin is actively transported into the bacterial cell via two different transport systems (the sn-glycerol-3-phosphate and hexose-6 transport systems).
Fosfomycin Eberth is indicated for:
- the treatment of acute, uncomplicated cystitis in women and female adolescents.